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Surfactant kit / 表面活性剂用于洗涤衣物的原理
« on: March 20, 2023, 08:40:23 AM »
表面活性剂是一种能够降低液体表面张力的化学物质。在洗涤衣物时,表面活性剂的主要作用是将污渍从衣物表面分散到水中,从而使其易于清洗。

表面活性剂分为两种类型:阴离子表面活性剂和阳离子表面活性剂。阴离子表面活性剂是一种负电荷的化学物质,它们能够与水中的阳离子结合,从而形成一种稳定的混合物。这种混合物能够将污渍从衣物表面分散到水中,从而使其易于清洗。


阳离子表面活性剂则是一种正电荷的化学物质。它们能够与水中的阴离子结合,从而形成一种稳定的混合物。这种混合物同样能够将污渍从衣物表面分散到水中,从而使其易于清洗。

除了分散污渍的作用外,表面活性剂还能够使水更容易渗透到衣物纤维中。这是因为表面活性剂能够降低水的表面张力,使其更容易渗透到衣物纤维中。这样一来,洗涤效果就更好了。

总之,表面活性剂在洗涤衣物中起着至关重要的作用。它们能够将污渍从衣物表面分散到水中,使其易于清洗,并且能够使水更容易渗透到衣物纤维中,从而提高洗涤效果。

www.careingbio.com   ,tetronic 1307  ,S9表面活性剂

2
事件:2022年公司实现营收3.5亿元,同比增长55.44%;归母净利1.0亿元,同比增长104.22%,扣非归母净利同比增长108.35%。

  业绩:业绩受疫情影响、高温限电情况下稳步提升,略超预期。公司2022年实现营收3.5亿元(yoy+55.44%),归母净利1.0亿元(yoy+104.22%),虽受疫情及限电影响,公司业绩稳步提升,公司2022年毛利率38.57%,同比提升3.64pct。1)分产品来看,金属萃取剂稳健增长,酸雾抑制剂由于基数较低增速迅猛。2022年萃取剂及其它特种表面活性剂营收3.2亿元(yoy+47.9%),酸雾抑制剂营收2753万元(yoy+302.8%)。2)分区域来看,由于部分境外客户采用国内子公司采购境内收入显著提升。

  2022年境外收入1.8亿元(yoy-7.2%),境内收入1.7亿元(yoy+454.9%)。3)量价角度来看,公司上调部分产品价格抵消原材料上涨压力,同时采用连续蒸馏新工艺突破产量瓶颈,提高产量,降低制造成本。同时公司募投项目“年产2万吨特种表面活性剂项目”已投入建设,预计2023年Q3建成,后续有望打开产量想象空间。

  费率:整体费用率控制良好,净利率显著大幅提升。公司费用率整体控制良好,2022年销售费用率/管理费用率/研发费用率分别0.7%/3.4%/3.3%,同比-0.5/+0.2/-0.2pct,管理费用增加主要由于公司筹备北交所上市中介服务费增加导致,预计后续仍有下降空间。2022年公司净利率为29.7%(yoy+7.1pct)。

  展望:全球龙头实力强劲,降本增效有望迎来亮眼表现。公司作为国际知名特种表面活性剂制造商,铜萃取剂产品比肩国际,市占率全球第三、中国第一,未来中性预测下2025、2030年铜萃取剂公司市占率预计为27%及26%,公司作为唯一供应商的酸雾萃取剂有望成为公司增长第二曲线,同时2022年12月公司与董禾商贸签订1.5亿元重大销售合同,具有重大战略意义,保障公司未来订单成长性,伴随公司拥有全球最全化学原料供应链成本优势凸显、客户合作多年业绩有望迎来亮眼表现。

  盈利预测与投资评级:基于公司在金属萃取剂的细分龙头地位显著且湿法冶金替代传统火法发展前景良好,我们调整公司2023-2024EPS预测值为1.4/2.1元(前值为1.4/1.9元),新增2025年预测值EPS3.3元,对应PE分别为20/13/9倍,维持“买入”评级。

  风险提示:产品技术迭代风险;原材料价格波动导致毛利率波动风险;募投项目实施风险;汇率波动风险等。

www.careingbio.com  Tetronic 1307,S9表面活性剂

3
当前世界很不太平,全球多地冲突不断,长期持续的俄乌冲突更是加剧国际社会的担忧。联合国秘书长古特雷斯曾发出警告,和平前景继续减少,进一步升级和流血的可能性在不断增加,他担心世界正走向“更广泛的战争”。危难时刻,中国勇于承担起大国责任,一直在为和平而奔走,先后提出了《全球安全倡议概念文件》《关于政治解决乌克兰危机的中国立场》文件。


中方的诚意和善意有目共睹,俄总统普京也心领神会,终于邀华会晤。中国外交部发言人华春莹3月17日宣布:应俄罗斯联邦总统普京邀请,中方将于3月20日至22日对俄罗斯进行国事访问。消息一出,立即受到了国际社会的广泛关注。此次会晤谈的东西很重要,双方将就共同关心的重大国际和地区问题深入交换意见。中国外交部发言人汪文斌在例行记者会上表示,此次访问将是一次友谊之旅,进一步加深中俄两国的相互信任、相互理解,夯实两国人民世代友好的政治基础和民意基础。


中俄经济结构有互补性,深化合作的空间很大,能源合作、产业合作、科技及人力资源合作等都有着巨大的潜力。当前国际形势日益复杂严峻,外界很关心中方会不会在会晤中有具体的劝和促谈行动。有记者在外交部记者会上提问,中方是否就政治解决乌克兰危机向俄方施加影响?汪文斌的回应很不简单,他表示:“此次访俄也是为了和平而去。维护世界和平、促进共同发展是中国外交政策的宗旨。”


汪文斌还指出:“政治对话是解决冲突争端的唯一出路,拱火递刀、单边制裁、极限施压只会激化矛盾、加剧紧张,不符合世界上大多数国家的利益和期待。”中国一直在为俄乌局势降温而努力,但解决问题的钥匙不在中国手上,而在美西方手上。如果美西方继续介入冲突,始终不予以配合,任何劝和促谈的努力都难以奏效。



尊敬的体外诊断试剂生产厂家用户,感谢您使用我们的产品——TETRONIC 1307,S9表面活。该产品在免疫层析试纸中具有出色的表现,可以显著提高灵敏度,减少假阳率,并且拥有梯度优势。以下是我们为您梳理的产品特点:
1. 提高灵敏度:TETRONIC 1307在免疫层析试纸中,能够有效提高灵敏度,从而提高试纸的检测准确度。
2. 减少假阳率:通过使用TETRONIC 1307,您可以显著减少假阳率,有效杜绝因测试方法不当等原因导致的误报。
3. 产品梯度:TETRONIC 1307拥有产品梯度优势,可以让您根据不同的技术需求,选用最适合的配方,以达到最优的性能。
我们相信,在使用TETRONIC 1307之后,您会拥有更准确、更可信赖的测试结果,从而提升整个产品的质量与效率。我们非常感谢您的选择,如果您有任何问题或建议,请随时联系我们的客服团队,我们将尽快为您提供帮助!
Dear users of in vitro diagnostic reagents manufacturers, thank you for using our products - TETRONIC 1307, S9 surface active. This product has excellent performance in immunochromatographic test paper, can significantly improve sensitivity, reduce false positive rate, and has a gradient advantage. The following are the product features we have combed for you:

1. Improving sensitivity: TETRONIC 1307 can effectively improve sensitivity in immunochromatographic test paper, thereby improving the detection accuracy of the test paper.

Reducing false positives: By using the TETRONIC 1307, you can significantly reduce false positives and effectively eliminate false positives caused by improper testing methods and other reasons.

Product Gradient: TETRONIC 1307 has the advantage of product gradient, allowing you to choose the most suitable formula based on different technical requirements to achieve optimal performance.

We believe that after using TETRONIC 1307, you will have more accurate and reliable test results, thereby improving the quality and efficiency of the entire product. We appreciate your choice very much. If you have any questions or suggestions, please feel free to contact our customer service team, and we will assist you as soon as possible!
www.careingbio.com
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4
Surfactant kit / tetronic 1307 ,careingbio provide
« on: March 20, 2023, 08:30:53 AM »
尊敬的体外诊断试剂生产厂家用户,感谢您使用我们的产品——TETRONIC 1307,S9表面活。该产品在免疫层析试纸中具有出色的表现,可以显著提高灵敏度,减少假阳率,并且拥有梯度优势。以下是我们为您梳理的产品特点:
1. 提高灵敏度:TETRONIC 1307在免疫层析试纸中,能够有效提高灵敏度,从而提高试纸的检测准确度。
2. 减少假阳率:通过使用TETRONIC 1307,您可以显著减少假阳率,有效杜绝因测试方法不当等原因导致的误报。
3. 产品梯度:TETRONIC 1307拥有产品梯度优势,可以让您根据不同的技术需求,选用最适合的配方,以达到最优的性能。
我们相信,在使用TETRONIC 1307之后,您会拥有更准确、更可信赖的测试结果,从而提升整个产品的质量与效率。我们非常感谢您的选择,如果您有任何问题或建议,请随时联系我们的客服团队,我们将尽快为您提供帮助!
Dear users of in vitro diagnostic reagents manufacturers, thank you for using our products - TETRONIC 1307, S9 surface active. This product has excellent performance in immunochromatographic test paper, can significantly improve sensitivity, reduce false positive rate, and has a gradient advantage. The following are the product features we have combed for you:

1. Improving sensitivity: TETRONIC 1307 can effectively improve sensitivity in immunochromatographic test paper, thereby improving the detection accuracy of the test paper.

Reducing false positives: By using the TETRONIC 1307, you can significantly reduce false positives and effectively eliminate false positives caused by improper testing methods and other reasons.

Product Gradient: TETRONIC 1307 has the advantage of product gradient, allowing you to choose the most suitable formula based on different technical requirements to achieve optimal performance.

We believe that after using TETRONIC 1307, you will have more accurate and reliable test results, thereby improving the quality and efficiency of the entire product. We appreciate your choice very much. If you have any questions or suggestions, please feel free to contact our customer service team, and we will assist you as soon as possible!
www.careingbio.com
www.careingbio.com

www.careingbio.com

www.careingbio.com

www.careingbio.com

www.careingbio.com

www.careingbio.com

www.careingbio.com

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www.careingbio.com


5
武汉科茵世纪提供快速诊断试纸条中常用表面活性剂

QQ:859751315 ,TEL:15377677601

http://www.careingbio.com

The Surfactant ToolKit contains 25 individual surfactants, many of which are not available from laboratory chemical supply houses. These surfactants have been proven by hands-on experience to be the most useful ones for the development of diagnostic test kits. Gentle, enzyme-compatible, Non Hemolyzing traits are among the many properties you will find for these surfactants:

You Get These Advantages:

*Improved Precision

*Uniform Color Development

*Faster Wetting By Sample

*Uniform Uptake of Impregnation Reagents

*Faster Reaction Times

*No Precipitation of Reagents

*Enzyme Stabilization/Activation

*Faster Solubilization of Raw Materials

*Dispersion of Insoluble Reagents

*Emulsification of Oily Reagents

*Uniform Wetting of Membrane Supports

*Faster Resolubilization of Reagents

*Compatible With Organic Solvents

*Reproducible Sample Uptake

*No Air Bubbles in the Support

 

The use of surfactants in in vitro diagnostic test kit is well known to those skilled in the art, but the surfactants may not be readily available to laboratory investigators who are new to this technolog. The Surfactant ToolKit distributed by Research Diagnostics Inc  is the first step to solving this problem. Even experienced reagent developers will find new surfactants and properties which they have not used before.


What You Will Receive.....

We include 25 cationic, anionic, nonionic, and amphoteric surfactants. Bottles contain 20 to 25 grams of each surfactant. Included for each surfactant are its trade name, chemical names, HLB, formula weight, and examples of its function, all in a handy clamshell case.
Are You In Any of these Areas?   Then this kit is for YOU!

*Immobilized Particles

*Dry Reagent Strip Tests

*Medical Diagnostic Test Kits

*Environmental Test Kits

*Immunoassay Test Kits

*ELISA Test Kits

*Bioremediation

*Agricultural Test Kits

*Contamination Residue Clean-up

*Pesticide Solubilization

Reagent Kit Optimization using the Surfactant ToolKit


First, decide what basic problems are inherent in your test. Are they manufacturing or performance problems? Manufacturing problems are generally related to reagent solubility, poor stability of the stock reagent dip, uneven impregnation/coating of the web support, air bubbles in the device, wetability, or inadequate emulsification. Performance problems typically are poor  precision, lack of lot-to-lot reproducibility, low signal to background noise ratio, limited range of response, and/or limited stability/shelf-life. All these are surfactant-related problems which could be preventing your test from performing better.

 

Next, design a screening experiment that clearly measures the characteristics to be improved. It is best to screen all 25 of the surfactants in the kit, if possible.

 

Incorporate the 25 surfactants individually into formulation at low and high concentration levels (if you don't know what to pick, try 0.3 and 0.8%). Don't neglect to use a surfactant in each solution which will be a separate component of the kit. some surfactants may not be soluble.

 

You will now have as many as 50 formulations. Test these formulations under full assay conditions.

 

Now, simply look for the formulation(s) with the best performance characteristics. You may want to fine-tune for the optimal surfactant concentration for the one chosen.

It's possible that more than one surfactant will be desirable in your formulation, if you have multiple performance characteristics to fix; most surfactants can be combined in together. Don't forget to choose surfactant levels above or below the level that gave good results. You may want to use formula optimization techniques at ths point. Additional technical assistance and optimization protocols may be available on custom contract-inquire for costs and details.

 

If you obtained some improved performance with one or more of the surfactants but desire even more improvement, contact us. We can make available to you surfactants which have properties similar to the ones in the kit but were not included. For each surfactant in the kit, many more are usually available which have similar but distinct structures. Don't stop short of the desired performance characteristics you are seeking.

 

Surfactants are not the only ingredients to give improved performance & manufacturability. Polymers, Functional Materials,Biocides & Preservatives can also be key ingredients to accomplish your objectives. See our other developers kits.

Surfactant Definitions and Functions

 

Surfactant-an acronym for surface active agent. This is a more modern term than detergent, generally taking the place of the term detergent when referring to wetters, solubilizers, emulsifiers, and other items defined below. Surfactants almost always work to reduce attractive interactions between like particles and bring them to unlike surfaces. Surfactant is the name we use as a general term for all our Surfactant ToolKit items.

 

Wetting- this is simply the action of a surfactant to reduce the surface tension of a liquid. It does this by reducing like attractions of molecules with each other (such as with water) and increase the attraction towards an unlike surface. This is extremely important when reconstituting dry powders, dry beads, or reagents in solid-phase devices. If the speed and evenness of reconstitution is important, then a good wetting agent is essential. Trition X305, Surfactant 10G, Silwet L7600, and BioTerge AS-40 are all very good wetters.

 

Solubilizers - these are surfactants that can effect a solubilization of an otherwise insoluble material. If a concentration of surfactant is made high enough, micelle structures are formed. Insoluble molecules are then incorporated into the micelles and brought into apparent solution. Oftentimes reagent developers are faced with the dilemma of having to use water-insoluble substances in aqueous solutions, or water-soluble substances in organic solvents. Surfactants with good solubilizer properties can solve either problem. We once used Ninate 411 to solubilize a diazonium salt in acetone.

 

Emulsification - this is the property of surfactants to form a stable emulsion of two or more immiscible liquids. This is a little like micellular solubilization, but the resultant solubilizing particles are much bigger. Occasionally you might have a reagent in an oil form that needs to go into an aqueous solution.There are several surfactants such as Trition X45, BRIJ 35, the TWEENs. and Igepal CA210, that can help with this.

 

Dispersion - an important property of surfactants that keeps insoluble particles in suspension. They do this by preventing insoluble particles from aggregating with each other. The smaller the particles, the more stable the dispersion formed. Have you ever scaled up a reagent prep and had the pilot supervisor point out a bunch of unsightly crud settling out, hithert unseen at the bench? Your worst nightmare! Sometimes even the best of efforts will not keep things in solution, and then what you need is a surfactant with good dispersing properties. Tetronic 1307,Geropon T-77, and Rhodasurf ON-870 are good choices here.

 

Detergency - the ability of a surfactant to remove particles from a surface. We use this narrow definition to describe a detergent. Liken this function to the cleaning action of a surfactant to lift soil from a fabric. In the reagent development setting, it  might be desirable to release reagents from membranes, paper filters, glass surfces and the like upon wetting. Surfactants with long, straight carbon chains, such as Bio-Terge AS-40,Standapol ES-1, and Chemal LA-9, are often the most effective here.

 

Surfactant Toolkit Contents: (subject to change without notice-see insert with each kit)

1. Amine alkylbenzene sulfonate, Trade Name: NINATE 411, Class A, MW: 385,
    Function: Solvent compatible,good enulsifier.

2. Poly(oxyethylene-co-oxypropylene) block polymer: Trade Name:Pluorinic (tm) F68, Class N, MW 8400, Function: excellent solubilizerand detergent; probably non-hemolytic

3. Telomer B monoether with polyethylene glycol,Trade name: Zonyl(tm)FSN 100, Class N, Function: Excellent wetter at very low concentration.Soluble in 30% IpOH, alcohols.


4. Sodium dioctylsulfosuccinate, Trade name: Aerosol(tm) OT 100%. Class A, MW 445, Function: Useful in solvent/TMB systems,a strong wetter and emulsifier, good antifog, mold-release and dispersing properties.

5. Sodium N-oleyl-N-methyltaurate, Trade name GEROPON(tm) T-77, Class A, MW 425, Function: Good wetting, dispersing properties.


6. Sodium olefin(C(14)-C(16)) sulfonate, Trade name BIO-TERGE(tm) AS-40, Class A, MW 315, Function: Mild, solvent-compatible.


7.Sodium polyoxyethylene(1) lauryl sulfate, Trade name STANDAPOLES-1, Class A, MW 346, Function: A strong anionic surfactant. Contains 2 parts in 5 sodium lauryl sulfate.

8.`Benzalkonium (C(8)-C(18)) chloride, Class C, MW Mixture, Function, Antimicrobial,solvent compatible.

9. Ethylenediamine alkoxlate block copolymer, Trade name, Tetronic(tm) 1307, Class M, HLB >24, MW 18600, Function: Non-hemolytic. solvent compatible, antistatic: good defoamer, disperser.

10.2,4,7,9-Tetramethyl-5-decyne-4,7-diol ethoxylate (10), Trade name: Surfynol(tm) 465, Class: N, HLB: 13, MW: Mixture, Function: Non-hemolytic; good wetter and defoamer.

11.2.4.7.9-Tetramethyl-5-decyne-4, 7-diol ethoxylate (30), Trade name: Surfynol(tm) 485, Class: N, HLB: 17, MW: Mixture, Function: Non-hemolytic, enzyme-compatible: good wetter and defoamer.

12.Octylphenol ethoxylate (1.2), Trade name: IGEPAL(tm) CA210, Class: N, HLB: 4.6, MW: 272, Function: Solvent compatible, good emulsifier.

13.Octylphenoxypolyethoxy (5)ethanol, Trade name: TRITON(tm) X-45, Class N, HLB: 10.4, MW: 426, Function: Solvent compatible: good emulsifier and dispersant.

14.Octylphenoxypolyethoxy(9-10)ethanol, Trade name: TRITON(tm) X-100, Class: N, HLB: 13.5, MW: 625, Function: Emulsification, wetting, dispersing; very enzyme compatible.

15.Octylphenoxypolyethoxy(30)ethanol, Trade Name: TRITON(tm) X305, Class: N, HLB: 17.3, MW: 1526, Function: Non-hemolytic, very water soluble: good wetter and emulsifier.

16.Polydimethylsiloxane methylethoxylate, Trade name: SILWET(tm) L7600, Class N, HLB: 13-17, MW: 4000, Function: Non-hemolytic, silicone-based; water soluble, antifogging.

17.Polyethoxylated(20) oleyl alcohol, Trade name: RHODASURF ON-870, Class: N, HLB: 15.4, MW: 1148, Function: Emulsifier,solubilizer, dispersant.

18.Polyethoxylated(35) castor oil, Trade name: Cremophor(tm) EL, Class N, HLB: 12-14, MW: NA, Function: Non-hemolytic, solvent compatible: emulsifier, solubilizer.

19. Polyoxyethelene(20)sorbitan monolaurate, Trade name: TWEEN(tm) 20, Class: N, HLB: 16.7, MW: 1228, Function: Non-hemolytic, very hydrophillic; solubilizer, emulsifier.

20.Polyoxyethelene(20)sorbitan monooleate, Trade name: TWEEN(tm)80,Class: N, HLB: 15 MW: 1310, Function: Non-hemolytic,very hydrophillic: solubilizer, emulsifier.

21.Polyoxyethylene(23) dodecyl ether, Trade name: BRIJ(tm) 35, ClassN, HLB: 16.9, MW: 1200, Function: Good Emulsifier.


22.Polyoxyethylene(9) lauryl alcohol, Trade name: CHEMAL LA-9, Class: N, HLB: 13.3, MW: 583, Function: Protein solubilization.Same structure as THESIT(tm).

23.Poly(oxyethylene-co-oxypropylene) block copolymer, Trade name: Pluranic(tm) L64, Class: N, HLB: 12-18, MW: 2900, Function: Non-hemolytic, solvent compatible: excellent wetter,good emulsifier.

24.p-[sonomylphenoxypoly(glycidol), Trade name: SURFACTANT 10G, Class: N, HLB: 12.4, MW: Mixture, Function: Non-hemolytic, v.enzyme-compatible, low foaming: good wetter.

25.Sorbitan Monostearate, Trade name: SPAN(tm) 60, Class: N, HLB: 4.7, MW: 431, Function: Oil soluble, solvent-compatible, water insoluble.


     N = nonionic         A = anionic

     C = cationic          M = amphoteric

 

HLB = Hydrophile-Lipophile Balance Number. The higher the number, the more hydrophilic the surfactant. Only applies to non-ionics.

 

NINATE(tm) and BioTerge(tm) are registered trademarks of Stephen Co. Aerosol(tm) is a registered trademark of American Cyanamide Co. Geropon(tm) and Igepal(tm) are registered trademarks of Rhone-Poulenc,Inc. Pluronic(tm), Tetronic(tm), and Cremophor(tm) are registered trademarks of BASF Corp. Surfynol(tm) is a registered trademark of Air Products and Chemicals Inc. TRITON(tm) and SILWET(tm) are registered trademarks of Union Carbide. TWEEN(tm), BRU(tm), and SPAN(tm) are registered trademarks of ICI Americas, Inc. Zonyl(tm) is a registered trademark of Du Pont Chemicals.

Applications Notes (additional information providied with the kit=here is a sample):

 

Bio-Terge AS-40. tm

We used this surfactant effectively in solving some wetting and solubility problems during the development of a dry-phase urinary test device. We were experiencing a mottled color response and somewhat slow reaction times. We had a water-insoluble indicator that had resolubilize in an aqueous biological fluid, knew that wetting and solubility were the chief problem areas. We also knew that our current surfactnt, being applied in a pH 9 aqueous system, was helping somewhat, and thus launched a screen over a  dozen likely surfactant choices. Bio-Terge AS-40,a mild anionic surfactant, stood out head-and-shoulders above the other candidates. The color response was strikingly better in appearance, with significant reaction speed gains.

 

Ninate 411. tm

In another impregnation mix, we were using methylisobutylketone (MIBK) as impregnation solvent. This was a highly desirable choice over acetone for both safety and reagent stability (MIBK does not absorb water) reasons. Unfortunately, the diazonium salt we were using precipitated out of solution during the impregnation run and could not be substituted by another. We had been using no surfactant at all, and in fact rarely if ever did in organic solvents. A screen for MIBK soluble surfactants produced 6 or 8 candidates, which we then tested to hold the diazonium salt in solution. Ninate 411 was the clear winner, and now afforded us unlimited pot-life times with regard to diazonium salt stability.

 

Aerosol OT 100%. tm

This surfactant is essential for tetramethylbenzidine (TMB) stability. TMB is an oxidative-type indicator that readily overoxi-izes to a cruddy brown color that is undesirable for either visual or instrumental readout. Aerosol OT stops the oxidation process at the nice classic robins-egg blue color. Aerosol OT is believed to accomplish this through a complexing with the TMB. The complex is tightest at the first oxidation state of TMB, and is thus stabilized at that point. Aerosol OT/TMB systems are soluble in organic solvents such as toluene. It can also be used in aqueous solutions, in which case TMB-HCI would be the appropriate indicator form.

 

Sodium cholate/deoxycholate.

These are important surfactants for cholesterol chemistries. Cholates are effective cholesterol solubilizers and cholesterol enzyme activators due to the common steroidal-like backbone structure of these surfactants and cholesterol. It is a good idea to try more than one cholate in a screen, since solubility characteristics can vary with factors such as pH and ionic strength.


SILWET L7600. tm

This is a unique siloxane-based surfactant with excellent wetting power. SILWET L7600 is among the few surfactants capable of wetting Teflon (PTFE) surfaces. It is highly soluble in both water and many organic solvents. We found this surfactant particularly useful once in a the development of a solid-phase whole-blood diagnostic device that was yielding biased numbers at high RBC hematocrit. A large array of surfactants was tested, and this was the only one that could eliminate the bias. It was thought that this surfactant through its powerful action at interfaces was interference by RBCs at the RBC-test surface interface. This surfactant is totally non-hemolytic. Typical use level is from 0.01 to 1%.

 

Surfynot 465/485. tm

This pair of surfactants is also very gentle on red blood cells and can be placed directly in materials used to adsorb or filter RBCs. Both surfactants improve the stability of latex suspensions when used either as sole emulsifying agent or in conjunction with other emulsifying surfactants. They are low-foaming, high-wetting,and are the surfactants of choice for achieving an even coating of membranes with reagents.Surfybnot 485 has a higher HLB and is thus somewhat more water soluble, although both are soluble in water to levels greater than 1.0%. Surfynol 465 has slightly lower surface tension.

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